BEHAVIOR OF TOTAL IGE AND SPECIFIC MARKERS OF ALLERGY SENSITIZATION IN A POPULATION OF THE CENTRAL VALLEY, COSTA RICA
Revista Ciencia y Salud / eISSN: 2215-4949 / https://revistacienciaysalud.ac.cr/ojs

Vol. 4 No. 1 (2020)Artículos

Vol. 4 No. 1 (2020)

BEHAVIOR OF TOTAL IGE AND SPECIFIC MARKERS OF ALLERGY SENSITIZATION IN A POPULATION OF THE CENTRAL VALLEY, COSTA RICA

Artículos

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Keywords

Hypersensitivity
allergy
allergen
atopy
Immunoglobulin E

How to Cite

Calderon trejos, O. (2020). BEHAVIOR OF TOTAL IGE AND SPECIFIC MARKERS OF ALLERGY SENSITIZATION IN A POPULATION OF THE CENTRAL VALLEY, COSTA RICA. Revista Ciencia Y Salud, 4(1), Pág. 4–21. https://doi.org/10.34192/cienciaysalud.v4i1.110

Abstract

Allergy is a hypersensitivity reaction initiated by

immunological mechanisms, either by antibodies

or by cells. In type I hypersensitivity the antibody

responsible is IgE. Atopy is the tendency to

sensitize and produce IgE antibodies in response

to allergen exposure. Allergens have been

classified into: inhalants, food, drugs, insects and

occupational. To make an adequate diagnosis

of allergic disease you must have a complete

medical history, physical evaluation, in vivo tests;

as well as in vitro tests such as the measurement

of specific IgE. Due to the limitations of skin tests,

as well as the need for a quick, simple, sensitive

and specific diagnosis, specific allergen tests are

used to identify sensitization. The behavior of the

data of specific allergens and total IgE, allows to

optimize the diagnostic protocols for the allergic

disease and that these become more effective,

able to reduce costs and that this information

helps the clinician in the first steps of allergic

disease, to manage and control the manifestations

and even eliminate or eradicate the disease. The

total IgE analysis indicates that practically half of

the data could be related to patients with type I

hypersensitivity, however, the negative values for

specific IgE are many compared to those positive

for food and inhalants except for mites Blomia

COMPORTAMIENTO DE LA IGE TOTAL Y DE MARCADORES ESPECÍFICOS DE

SENSIBILIZACIÓN ALÉRGICA EN UNA POBLACIÓN DEL VALLE COSTA RICA

BEHAVIOR OF TOTAL IGE AND SPECIFIC MARKERS OF ALLERGY SENSITIZATION IN A

POPULATION OF THE CENTRAL VALLEY, COSTA RICA

Calderón Trejos, Óscar ; Monge Ocampo, Jeremías y Sánchez Barahona, María Fernanda,

San José, Costa Rica, Hospital de las Mujeres Adolfo Carit Eva

Pág. 4,21

Recibido: 20 Enero 2020

Aceptado: 25 Enero 2020

4

Integrando Conocimientos Revista Ciencia & Salud: Integrando Conocimientos / Febrero - Marzo 2020 / Volumen 4 / Número 1

3

tropiclais, Dermatophagoydes pteronyssinus

and Dermatophagoydes farinae. Perform a

measurement of total IgE as well as specific

allergens such as allergic disease screening,

should be performed with caution, taking into

account the limitations of these techniques

Keywords: Hypersensitivity

https://doi.org/10.34192/cienciaysalud.v4i1.110
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