Abstract
Allergy is a hypersensitivity reaction initiated by
immunological mechanisms, either by antibodies
or by cells. In type I hypersensitivity the antibody
responsible is IgE. Atopy is the tendency to
sensitize and produce IgE antibodies in response
to allergen exposure. Allergens have been
classified into: inhalants, food, drugs, insects and
occupational. To make an adequate diagnosis
of allergic disease you must have a complete
medical history, physical evaluation, in vivo tests;
as well as in vitro tests such as the measurement
of specific IgE. Due to the limitations of skin tests,
as well as the need for a quick, simple, sensitive
and specific diagnosis, specific allergen tests are
used to identify sensitization. The behavior of the
data of specific allergens and total IgE, allows to
optimize the diagnostic protocols for the allergic
disease and that these become more effective,
able to reduce costs and that this information
helps the clinician in the first steps of allergic
disease, to manage and control the manifestations
and even eliminate or eradicate the disease. The
total IgE analysis indicates that practically half of
the data could be related to patients with type I
hypersensitivity, however, the negative values for
specific IgE are many compared to those positive
for food and inhalants except for mites Blomia
COMPORTAMIENTO DE LA IGE TOTAL Y DE MARCADORES ESPECÍFICOS DE
SENSIBILIZACIÓN ALÉRGICA EN UNA POBLACIÓN DEL VALLE COSTA RICA
BEHAVIOR OF TOTAL IGE AND SPECIFIC MARKERS OF ALLERGY SENSITIZATION IN A
POPULATION OF THE CENTRAL VALLEY, COSTA RICA
Calderón Trejos, Óscar ; Monge Ocampo, Jeremías y Sánchez Barahona, María Fernanda,
San José, Costa Rica, Hospital de las Mujeres Adolfo Carit Eva
Pág. 4,21
Recibido: 20 Enero 2020
Aceptado: 25 Enero 2020
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Integrando Conocimientos Revista Ciencia & Salud: Integrando Conocimientos / Febrero - Marzo 2020 / Volumen 4 / Número 1
3
tropiclais, Dermatophagoydes pteronyssinus
and Dermatophagoydes farinae. Perform a
measurement of total IgE as well as specific
allergens such as allergic disease screening,
should be performed with caution, taking into
account the limitations of these techniques
Keywords: Hypersensitivity
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