Enfermedad atípica: Inmunodeficiencia combinada grave

Abstract

Severe combined immunodeficiency is a hereditary disease linked to the X chromosome where there are abnormalities in the functions of T, B and NK lymphocytes, which can be mixed and affect two or more of these cell populations, there is still no extensive registry of this disease, given that it has a very low incidence, and despite having no cure, its prognosis is relatively favorable if it is detected early. Currently there are some treatments to improve the quality of life of the patient such as bone marrow transplantation or intravenous immunoglobulin replacement (IGIV), this review aims to explain the processes involved in the development of this disease