Adaptive immunity induced by Bacillus Calmette-Guérin and its relationship with COVID-19.
Revista Ciencia y Salud / eISSN: 2215-4949 / https://revistacienciaysalud.ac.cr/ojs

Vol. 7 No. 3 (2023)Artículos

Vol. 7 No. 3 (2023)

Adaptive immunity induced by Bacillus Calmette-Guérin and its relationship with COVID-19.

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Keywords

vacuna BCG
Calmette-Guerín Bacillus
COVID-19 enfermedad viral
SARS-CoV-2
efectos heterólogos de las vacunas

How to Cite

Ordóñez Andrade, P., & Coyago Iñiguez, J. A. (2023). Adaptive immunity induced by Bacillus Calmette-Guérin and its relationship with COVID-19. Revista Ciencia Y Salud, 7(3), 119–127. https://doi.org/10.34192/cienciaysalud.v7i3.684

Abstract

ABSTRACT

COVID-19, caused by SARS-CoV-2, has been a worrying factor in mortality worldwide, so several innovative approaches are being developed to slow the spread of SARS-CoV-2. In particular, BCG, the tuberculosis vaccine, is being considered as an alternative therapeutic modality. BCG vaccine is known to induce both humoral and adaptive immunity, thus activating non-specific and cross-reactive immune responses in the host, which in combination could effectively resist other pathogens, including SARS-CoV-2. In this review we intend to describe based on the review of the literature; if prior BCG vaccination influences the mortality rates of COVID-19, thus seeking to expand scientific knowledge, in addition to stating whether it will contribute to the fight against COVID-19, and may be ideal in this context due to its low cost, and wide distribution. The literature suggests that there is a lower mortality rate in countries with a prolonged national BCG vaccination program, and this also contributes to reducing infant and adult mortality rates over 45 years of age, mediated by non-specific immunity.

https://doi.org/10.34192/cienciaysalud.v7i3.684
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Copyright (c) 2023 Pablo Ordóñez Andrade, Juan Antonio Coyago Iñiguez

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