Supplementary Files
Keywords
heart failure
advanced chronic heart failure
acute descompesation
Levosimendan
intermittent treatment
inodilator
inotropic treatment
cardio protective
advanced chronic heart failure
acute descompesation
Levosimendan
intermittent treatment
inodilator
inotropic treatment
cardio protective
How to Cite
1.
González Quesada AP, Badilla Casasola A, Arroyo Quirós MA, Gutiérrez Castro DM. Use of Levosimendan in Acute Heart Failure and Advanced Chronic Heart Failure: evidence review: Definition of Advanced Chronic Heart Failure. Rev Cienc Salud Integr Conoc [Internet]. 2022 Dec. 16 [cited 2026 Sep. 20];6(6):1-18. Available from: https://revistacienciaysalud.ac.cr/ojs/index.php/cienciaysalud/article/view/432
Abstract
Levosimendan is an inodilator characterized by its positive inotropy, vasodilation, and cardioprotection; uniquemechanism of action that differentiates it from all other inotropic drugs. In addition, it has the active
metabolite, OR-1896, which allows it to maintain its therapeutic effects for several days, even after the
infusion is finished. Its potential effects to manage acute heart failure and advanced chronic heart failure have now been
demonstrated, providing a new option for patients when conventional therapy is not being effective in
controlling the disease.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2022 Andrea González Quesada, Alexa Badilla Casasola, Alejandra Arroyo Quirós, Douglas Gutiérrez Castro
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