Abstract
A 50-year-old male patient with De Quervain’s tenosynovitis, who, after initial management with nonsteroidal anti-inflammatory drugs and an infiltration with betamethasone (5 mg dipropionate and 2 mg sodium phosphate) that provided only transient relief, received a second infiltration with triamcinolone acetonide. Approximately two months after the procedure, a hypopigmented lesion with irregular borders appeared at the injection site. This manifestation represents an underrecognized adverse effect of corticosteroid infiltrations. This case underscores the importance of primary care professionals to consider this adverse effect, and that patients are appropriately informed about the possible local complications, including pigmentary changes, as well as considering its psychological and aesthetic impact.

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2026 Andrea Balmaceda Meza, Jimena Meléndez Quintero

